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I have been using this medication almost since it came on the market. I take a dose of 50% over the maximum recommended dosage. The medication seems to have a 7-10 hours effectiveness before rebound symptoms appear. I've tried several of the other proton pump inhibitors, which were not very effective.



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In a 1-year study of GERD patients treated with Pantoprazole 40 mg or 20 mg, there were no changes from baseline in overall levels of T 3, T 4, and TSH.

In this study pantoprazole 40 mg once daily or placebo was administered for 12 weeks to patients requiring long-term NSAIDs.

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Gastroesophageal Reflux Disease () and Zollinger-Ellison Syndrome are the two main conditions that it is used to treat.

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